As with a traditional differential extraction, the epithelial cells are lysed and the sperm cells are pelleted. After removing the epithelial DNA for testing, the remaining epithelial cell DNA is destroyed while leaving the sperm cells intact. It is possible to destroy all of the epithelial DNA even when there are a relatively small number of sperm cells and overwhelming quantities of epithelial DNA. This method eliminates mixture profiles in nearly all cases.

NIJ Conference 2011 Poster: Differential Extractions

NIJ Conference 2012 Poster: Casework and Substrate Experience

How It Works
Partially funded by NIJ Grant 2009-DN-BX-K039